Crohn’s disease causes inflammation in the gastrointestinal (GI) tract. It most commonly affects the small intestine and the beginning of the large intestine, however it can affect any part of the GI tract from the mouth to the anus. 

Granulomatous colitis, also known as Crohn's colitis, occurs only in the colon (also known as the large intestine or large bowel). It is often just known as Crohn’s colitis and is a form of Crohn’s disease. It accounts for around 20% of Crohn’s disease cases.

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